20 South Sarah Street St. Louis, MO 63108 314-615-6355 info@biogenerator.org

Portfolio

Portfolio Summary

BioGenerator creates, grows and invests in promising bioscience companies and entrepreneurs. Our portfolio consists of staged investments, where increasing amounts of capital are deployed in the most promising companies. BioGenerator has invested $15.2 million and our portfolio companies have raised $462 million in follow-on funding. In addition to investments, BioGenerator supports promising early stage opportunities through grants.

Active Investments

Accuronix Therapeutics is developing breakthrough treatments for the most difficult types of cancer. With a particular focus in pancreatic cancer, the company’s mission is to develop novel oncology therapies founded on technology that selectively targets overexpressed receptors on cancer cells.

Sector: Therapeutics

×

Adarza BioSystems is a label-free platform technology that enables the simultaneous detection of hundreds of proteins in a single drop of blood—at an industry-leading low cost. The company has developed the only next generation immunoassay platform proven capable of sensitive and reproducible highly multiplexed protein detection.

Visit Adarza BioSystems Website

Sector: Research Tools

×

RNAgri is a startup making huge progress in RNA production and RNAi products. RNAi, which is an abbreviation for RNA interference, is a technology that relies on gene regulation without the heritable effects of DNA. Because RNAi works downstream from DNA, it is not genetic modification and therefore is non-GMO. RNAgri has developed technology that will allow the cost efficient production of RNA for broad acre topical RNAi uses in agriculture.

Visit the RNAgri website. 

Sector: Agriculture

×

Arch Innotek produces high-value natural ingredients for human and animal health by low-cost, sustainable fermentation-based processes.

Visit the Arch Innotek website

Sector: Agriculture

×

Arvegenix is developing Field Pennycress to be the next major crop in the Midwest. Pennycress produces economically important meal and oil, while providing winter cover crop benefits by preventing soil erosion and protecting from nitrogen runoff.

Visit ARVEGENIX website 

Sector: Agriculture

×
atomation IOT platform smart objects

Atomation is developing an IOT platform of SHDK (software & hardware development kit) for the seamless creation of smart objects

Visit Atomation website

×

BacterioScan is commercializing electro-optic instruments and disposables for rapidly detecting and measuring the concentration and growth of bacteria in fluids for research
and medical diagnostic applications. The technology will reduce the cost and delay of UTI diagnosis, and is expected to also reduce the unwarranted use of antibiotics.

Visit BacterioScan Website

Sector: Medical Devices

×

Benson Hill Biosystems is an agricultural biotechnology company focused on developing biotech-based traits to increase intrinsic crop yields, principally by enhancing photosynthetic efficiency.

Visit Benson Hill Biosystems Website

Sector: Agriculture

×
Canopy Biosciences

Canopy Biosciences is a source for cutting edge research tools for genetic engineering, molecular biology, and personalized medicine. They partner with leading researchers at top institutions to turn their discoveries into tangible products, and make them available to the world.

Sector: Research Tools

×
Cardialen medical device

Cardialen is revolutionizing atrial and ventricular disease treatment by offering a low energy therapy, released from an implantable device.

Visit Cardialen Website

Sector: Medical Devices

×

Cofactor Genomics is the market leader in RNA based products and services in the rapidly expanding functional genomics market.

Visit the Cofactor Genomics website 

Sector: Contract Research Organization

×

Daya CNS is developing novel therapeutics for the treatment of neuropathic pain.

Sector: Therapeutics

×

Edison Agrosciences is an agricultural biotechnology company dedicated to developing and commercializing innovative solutions for the production of plant-based industrial materials, with a primary focus on the development of alternative rubber crops.

Visit Edison Agrosciences website 

Sector: Agriculture

×

Electrochaea developing a game-changing technology for grid-scale energy storage by partnering with leading utilities and grid operators in Europe.

Visit Electrochaea Website

Sector: Other

×

Elira Therapeutics is a medical device company developing a novel system to suppress appetite and assist with diet adherence.

Sector: Medical Devices

×

ePharmix offers a portfolio of prescribable, disease-specific communication tools designed by practicing providers to improve their patients’ health.

Visit Epharmix’ website

Sector: Health IT

×

Euclises is developing patient stratified, novel, oral drugs for the treatment of COX-2 activated, refractory and resistant cancers.

Visit Euclises Pharmaceuticals Website

Sector: Therapeutics

×

Galera Therapeutics is focused on the development of breakthrough drugs targeting the oxygen metabolic pathways. The company’s lead compounds are small molecule dismutase mimetics which prevent radiation-induced toxicity, and may also be used for treatment of fibrotic diseases and cancer.

Visit Galera Therapeutics Website

Sector: Therapeutics

×

GeneriCo is developing and marketing generic pharmaceuticals in significant specialty segments of the rapidly growing generic drug market.

Visit GeneriCo Website

Sector: Therapeutics

×

Graematter has created a proprietary information analytics system that consolidates information from a significant—and growing—number of FDA sources into a single database with advanced search capabilities.

Visit Graematter Website

Sector: Health IT

×

Immunophotonics is developing an in situ therapeutic cancer vaccine for the treatment of solid tumor cancers. The technology is practical, cost-effective, nontoxic and potentially highly effective, as indicated by nonclinical and initial clinical studies.

Visit Immunophotonics Website

Sector: Therapeutics

×
Indalo Therapeutics

Indalo Therapeutics is a preclinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating fibrotic diseases. Founded on groundbreaking scientific discoveries and leveraging cutting-edge insight into the molecular drivers of aberrant scarring, Indalo is harnessing the collective experience of a seasoned team of pharmaceutical scientists and executives to tackle some of the most urgent unmet medical needs in the fibrosis space.

Visit Indalo Therapeutics Website

Sector: Therapeutics

×

Katalyst Surgical is an industry leader in titanium ophthalmic surgical instruments, and ophthalmic eye instruments.

Visit the Katalyst website

Sector: Medical Devices

×

Kogent Surgical is a designer and manufacturer of neurosurgery titanium instruments, mono/bipolar RF Generators, true non-stick bipolar forceps, ultrasonic aspirators with true bone removal capability, and other important novel tools and devices.

Visit Kogent Surgical Website

Sector: Medical Devices

×

Kypha is a medical diagnostics startup developing products to improve the way inflammation and autoimmune diseases are monitored and treated. Kypha is advancing its point-of-care diagnostics platform toward regulatory clearance and market launch.

Visit Kypha Website

Sector: Diagnostics

×

MedAware offers a comprehensive solution for empowering care teams, patients and family to overcome the inherent challenges of care coordination which is estimated to cost our health system $240B today. The company focuses on transforming the healthcare communication experience across settings of care in a rapidly growing marketplace.

Visit the MedAware website

Sector: Health IT

×

MediBeacon is a medical device company focused on providing critical, real-time renal information to clinicians to measurably improve patient care. MediBeacon’s Optical Renal Function Monitor allows for real-time monitoring of kidney function at the point of care, providing direct, accurate, and current information.

Visit MediBeacon Website

Sector: Medical Devices

×

MedSocket was built for the growing need of healthcare organizations to provide quick access to clinical decision support information at the point of care.

Visit MedSocket website 

Sector: Health IT

×

Mobius Therapeutics has developed a novel, patent protected kit system, Mitosol®, for delivering mitomycin-c in glaucoma, surface ablation, and pterygium surgeries. Mobius obtained FDA approval for glaucoma surgery through a 505(b)(2) NDA process and is pursuing sNDA’s for additional indications.

Visit Mobius Therapeutics Website

Sector: Therapeutics

×

Nanopore Diagnostics is a molecular diagnostics company developing a rapid, portable platform technology that quickly and accurately quantifies biomarkers and microorganisms in a raw fluid sample.

Visit Nanopore Diagnostics Website

Sector: Diagnostics

×

Neurolutions seeks to develop a revolutionary platform of devices, based on Brain Computer Interface technology, which promise to restore function to patients who are disabled as a result of neurological injury.

Visit Neurolutions Website

Sector: Medical Devices

×

Nitrogenics has modified plants to allow direct absorption of atmospheric nitrogen rather than from fertilized soil.

Sector: Agriculture

×
Plastomics biotech crops

Plastomics is a biotechnology start-up using precision engineering to develop high performance crops.

View Plastomics Website

Sector: Agriculture

×

PMDI is a partnership between the Peter Michael Foundation and The Genome Institute at Washington University School of Medicine that will commercialize breakthrough research for prostate cancer.

Sector: Diagnostics

×

Pulse Therapeutics has developed a new approach to improve the fluid dynamics in poor to zero flow vascular anatomical locations, with potential application in stroke and DVT.

Visit Pulse Therapeutics Website

Sector: Medical Devices

×

S4 Agtech uses satellite images of farm fields around the world and data analytics to help its customers predict crop yields, allowing them to make more informed decisions and better allocate their resources.

Visit the S4 website

Sector: Agriculture

×
SentiAR augmented reality medical

SentiAR is developing augmented reality technology to improve medical procedures.

View SentiAR Website

×

Tioma is developing humanized anti-CD47 monoclonal antibodies for multiple human diseases that will benefit from modulation of CD47 activity.

Visit Tioma Website

Sector: Therapeutics

×

Unleash is an immune-oncology company developing virus immunotherapy products to treat cancer.

Visit Unleash’s website

Sector: Therapeutics

×

YourBevCo is marketing novel consumer products that remove allergens and other problematic ingredients from foods and beverages.

Visit YourBevCo Website

Sector: Consumer Packaged Goods

×

Investment Exits

Apertus Pharmaceuticals specializes in the manufacturing of Active Pharmaceutical Intermediates for Class II-V controlled substances. It also has related business streams for Drug Discovery Services and Analytical Services that leverage internal expertise and capabilities.

Visit Apertus Pharmaceuticals Website

Sector: Contract Research Organization

×

APT Therapeutics is a potential new treatment for acute thrombotic diseases with a combination of potent anti-thrombotic and anti-inflammatory efficacy, fast onset of action, and no bleeding.

Visit APT Therapeutics Website

Sector: Therapeutics

×

Array Bridge provides products and services that address two important areas in the development of biologics: biosimilar and innovator drug comparability analysis and impurity analysis.

Visit Array Bridge Website

Sector: Research Tools

×

Confluence Discovery Technologies is a drug discovery and development contract research organization providing biochemistry, biomarker, target validation and other services to pharma and academic clients.

Visit Confluence Discovery Website

Sector: Contract Research Organization

×

Confluence Life Sciences is a drug discovery and development company focusing on rational drug design to identify proprietary, mechanistically novel drugs. The company has developed a portfolio of projects to address unmet medical needs in cancer and chronic inflammatory diseases.

Visit Confluence Life Sciences Website

Sector: Therapeutics

×

SynerZ Medical is a medical device company focused on the treatment of obesity, type 2 diabetes and other metabolic syndromes.

 

Sector: Medical Devices

×

BioGenerator Grants

Agrela Ecosystems

View Agrela Ecosystems Website

Sector: Agriculture

×

Therapeutic antibodies for autoinflammatory disease and cancer

Sector: Therapeutics

×

Neuroegeneration therapeutics

Sector: Therapeutics

×

Research instrument to directly assess mitochoncrial function

Sector: Research Tools

×

Sector: Diagnostics

×

Medical device for treatment of cardiac diseases

Sector: Medical Devices

×
Cellatrix biotechnology research tools

Drug discovery research tools and services

View Cellatrix Website

Sector: Research Tools

×
Disarm Therapeutics biotechnology

Disarm Therapeutics is developing therapeutics to treat patients with neurological diseases by preventing axonal degeneration.

View Disarm Website

Sector: Therapeutics

×
Fimbrion therapeutics biotechnology

Antibacterials

View Fimbrion Website

Sector: Therapeutics

×

View Gateway Pharma Website

Sector: Therapeutics

×

Device to reduce costs associated with intravenous procedures

Sector: Medical Devices

×

Molecular diagnostics for cancer and GI diseases

View Geneoscopy Website

Sector: Diagnostics

×

Novel diagnostic technology

Sector: Health IT

×
KaloCyte therapeutics biotechnology

Blood substitute technology

View KaloCyte website

Sector: Therapeutics

×

Research tools associated with kinases

Sector: Research Tools

×

Sector: Research Tools

×

Cancer therapeutics

Sector: Diagnostics

×

Improved surgical device

Sector: Medical Devices

×

Novel antibacterials

Sector: Therapeutics

×
Precision Virologics biotechnology

Viral therapies

View Precision Virologics Website

Sector: Therapeutics

×
Pro-Arc Diagnostics biotech

Molecular diagnostics for inflammatory diseases

View Pro-Arc Diagnostics Website

Sector: Diagnostics

×

Sector: Therapeutics

×

Provetis is a collaboration of leading scientists and commercialization experts to create new veterinary drugs and products for companion and production animals.

Sector: Other

×

Innovative devices for research use

Sector: Research Tools

×

Sector: Research Tools

×

Sector: Consumer Packaged Goods

×

Technology development

Sector: Therapeutics

×
Viosera Therapeutics biotech

New antibacterial technology

View Viosera Therapeutics Website

Sector: Therapeutics

×

View Where4Care Website

Sector: Health IT

×

Sector: Diagnostics

×

Getting Started

Entrepreneurs Investors